Take a gander at the exciting news from ME Australia! Japanese researchers have found a biomarker for ME/CFS that also proves that our fatigue IS PATHOLOGICAL and not somehow psychological. They also did the same for major depressive disorder. This is going to set the world of ME/CFS research on fire and I look forward to witnessing the chain reaction.
Of course it’s important to understand that it doesn’t tell us what causes CFS or point us toward a cure. It isn’t even “the biomarker” to end all biomarkers, because it behaves the same way with other conditions, therefore it doesn’t exclude them, but it is actual, verifiable, scientific, diagnostic criteria. Combining biomarker testing with existing criteria would make for much stronger, more accurate diagnosis. I wager it would also be much more affordable than the ideas surrounding imaging that are currently underg oing testing and could work well as a precursor to such tests.
For more specifics, read on:
Researchers in Japan measured salivary human herpesvirus HHV-6 and HHV-7 and found they can be used as biomarkers to tell the difference between physiological (recovers with rest) fatigue and pathological fatigue.
In healthy people, HHV-6 and HHV-7 increased with training and work then rapidly decreased with rest. In people with chronic fatigue syndrome (CFS Fukuda criteria), obstructive sleep apnea syndrome and major depressive disorder, HHV-6 and HHV-7 did not increase.